Part of the PTSD Questions cluster.
What Is PTSD?
Post-Traumatic Stress Disorder (PTSD) is not a character weakness or a failure to "move on." It is a neurobiological injury caused by exposure to actual or threatened death, serious injury, or sexual violence. Symptoms cluster around four domains: intrusive re-experiencing, avoidance, negative alteration in mood/cognition, and altered arousal.
PTSD emerges when a traumatic event exceeds the nervous system capacity to process it. The amygdala becomes sensitized, the prefrontal cortex shows reduced activation, and the hippocampus experiences volume loss.
PTSD vs Complex PTSD
While PTSD results from single-incident trauma, C-PTSD develops from prolonged, repeated interpersonal trauma. The WHO recognized C-PTSD in ICD-11 in 2018. C-PTSD includes all PTSD symptoms plus emotional dysregulation, negative self-perception, difficulty with relationships, and dissociation.
"Traumatized people are not simply people who have had a bad experience. They are people whose neurobiology was rewired by an event that shattered their basic sense of safety."
Neuroscience
The amygdala (threat detector) becomes hyperactive, the hippocampus loses volume (explaining why flashbacks feel like "now"), and the prefrontal cortex is dampened. Dr. Bessel van der Kolk demonstrated that trauma memories are stored as fragmented sensory fragments, not coherent narratives.
Evidence-Based Treatments
Trauma-focused psychotherapies include EMDR, CPT, and Prolonged Exposure. Somatic approaches like Somatic Experiencing and Sensorimotor Psychotherapy work with the body. Emerging treatments include MDMA-assisted therapy (67% remission rate in Phase 2 trials for severe PTSD) and Stellate Ganglion Block.
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Start Your Reset →Research References
This content draws on established research in mental health, clinical psychology, and trauma-informed care.
Primary Research
- Van der Kolk, B. (2014) — The Body Keeps the Score (PubMed)
- Cloitre et al. (2016) — ICD-11 Complex PTSD (PubMed)
- Mitchell et al. (2017) — MDMA-Assisted Therapy for PTSD (PubMed)
